Search results for "Leukemia P388"

showing 3 items of 3 documents

Gamma interferon administration differently affects sensitive or doxorubicin resistant P388 leukemia cells; a relationship with antioxidant defenses?

1989

Antioxidantmedicine.medical_treatmentDrug ResistanceDrug resistancePharmacologyBiologyAntioxidantsInterferon-gammaMiceGamma interferonTumor Cells CulturedmedicineAnimalsInterferon gammaDoxorubicinPharmacologyLeukemia ExperimentalLeukemia P388medicine.diseaseGlutathioneIn vitroLeukemiaCytokineDoxorubicinMice Inbred DBAmedicine.drugPharmacological Research
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Dynamic Antigen Presentation Patterns of Listeria monocytogenes-Derived CD8 T Cell Epitopes In Vivo

2001

Abstract Little information exists regarding the presentation of antigenic peptides in infected tissues. In this study the in vivo presentation of four different CD8 T cell epitopes of Listeria monocytogenes was monitored. Peptide presentation was measured by a new, highly sensitive, ex vivo Ag presentation assay that was based on the testing of freshly isolated cells from infected spleens with peptide-specific CD8 T cell lines in an IFN-γ-specific ELISPOT assay. Remarkably, the peptide presentation pattern of splenocytes and that of macrophages purified from spleens of L. monocytogenes-infected mice were different from those of in vitro infected macrophage-like cell lines. The in vivo Ag p…

Bacterial ToxinsImmunologyAntigen presentationEpitopes T-LymphocyteEnzyme-Linked Immunosorbent AssayCD8-Positive T-LymphocytesBiologyEpitopeHemolysin ProteinsMiceBacterial ProteinsIn vivoTumor Cells CulturedAnimalsImmunology and AllergyCytotoxic T cellLymphocyte CountAntigen-presenting cellHeat-Shock ProteinsAntigen PresentationLeukemia P388MacrophagesELISPOTListeria monocytogenesVirologyPeptide FragmentsKineticsOrgan SpecificityCell cultureInjections IntravenousFemaleSpleenEx vivoThe Journal of Immunology
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Number and functionality of beta-adrenergic receptors in the mouse lymphocytic P388 leukemia as a doxorubicin-sensitive and -resistant variant.

1992

Pharmacologymedicine.medical_specialtyAdrenergic receptorChemistryLeukemia P388Adrenergic beta-AntagonistsColforsinDrug ResistanceAlpha-1B adrenergic receptorAlpha-1A adrenergic receptorMiceEndocrinologyDoxorubicinInternal medicinePindololmedicineCancer researchCyclic AMPAnimalsDoxorubicinP388 leukemiaAlpha-1D adrenergic receptorReceptormedicine.drugPharmacological research
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